CD133 Antigen (AA 836-865) antibody

Catalog No. ABIN7091860

The Rabbit Polyclonal anti- antibody has been validated for WB, FACS, ELISA, IHC (fro), IHC (p) and IF. It is suitable to detect in samples from Human and Mouse.

Quick Overview for CD133 Antigen (AA 836-865) antibody (ABIN7091860)

Target: CD133 Antigen

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: Un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Product Details

Binding Specificity: AA 836-865

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Fruit Fly

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CD133 antigen

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
FCM 1:20-100
IHC-P 1:200-400
IHC-F 1:100-500
IF()

Restrictions: For Research Use only

Handling

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details

Target: CD133 Antigen

Background:

Synonyms: AC133, Antigen AC133, Hematopoietic stem cell antigen, hProminin, PROM1, Prominin I, Prominin like protein 1 precursor, Prominin mouse like 1, prominin1, PROML1, CD133, CORD12, MCDR2, MSTP061, PROML1, RP41, STGD4, PROM1_HUMAN.

Background: Binds cholesterol in cholesterol-containing plasma membrane microdomains. Proposed to play a role in apical plasma membrane organization of epithelial cells. During early retinal development acts as a key regulator of disk morphogenesis. Involved in regulation of MAPK and Akt signaling pathways. In neuroblastoma cells suppresses cell differentiation such as neurite outgrowth in a RET-dependent manner.

Gene ID: 8842

UniProt: O43490